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Hotels in Cape Girardeau, Missouri

Only Handpicked and Verified Accommodations for Your Stay in Cape Girardeau, Missouri

Check-in
24Oct
Check-out
25Oct
Guests
2 Guests
Cape Girardeau features the vibrant River Walk, the historic Cape Riverfront, and the bustling Isle of Capri Casino. You'll find plenty to see at the Cape Girardeau Conservation Nature Center and the scenic Trail of Tears State Park. For accommodations, local hotels offer diverse options, from cozy inns to modern places with riverside views. Each hotel is carefully selected based on guest reviews and standout amenities. When booking, consider visiting during fall for pleasant weather and easy access to attractions. Public transport options are available for easy city navigation.
All filters
1-20 out of 25
Sort by:high popularity
  • Price: low to high
  • Price: high to low
  • Guest rating: high to low
  • Popularity: high to low
Pear Tree Inn Cape Girardeau Medical Center
8.2
Great
Pear Tree Inn Cape Girardeau Medical Center
MapClose to restaurants300m
  • Free continental breakfast served daily
  • Pets allowed for added convenience
  • Wheelchair access for ease of movement
  • 24-hour reception
  • Restaurant
  • Flat-screen TV
Hotel with free breakfast and pet-friendly rooms
FromUS$ 75 /nightSelect
Drury Plaza Hotel Cape Girardeau Conference Center
8.4
Great
Drury Plaza Hotel Cape Girardeau Conference Center
MapRight off the interstate0m
  • Indoor pool with hot tub
  • Buffet breakfast served daily
  • Fitness center available on-site
  • Indoor pool
  • Fitness center
  • Hot tub
Hotel featuring modern rooms and extensive wellness amenities
FromUS$ 115 /nightSelect
Pear Tree Inn Cape Girardeau West
8.4
Great
Pear Tree Inn Cape Girardeau West
MapNearby shopping malls300m
  • Daily buffet breakfast included
  • Close to shopping and dining options
  • 24-hour front desk service available
  • Free parking
  • Business centre
  • Fitness centre
Hotel offering comfortable rooms near local attractions
FromUS$ 70 /nightSelect
Drury Inn & Suites Cape Girardeau
8.4
Great
Drury Inn & Suites Cape Girardeau
MapProximity to shopping and dining300m
  • Indoor swimming pool access for families
  • Complimentary breakfast buffet served daily
  • Free evening Kickback meals offered
  • Indoor Pool
  • Fitness Centre
  • Hot Tub
Hotel featuring a family-friendly atmosphere and amenities
FromUS$ 73 /nightSelect
Auburn Place Hotel & Suites Cape Girardeau
8.4
Great
Auburn Place Hotel & Suites Cape Girardeau
MapAdjacent to Westfield Shopping Mall100m
  • Indoor pool and hot tub available
  • On-site fitness center for guests
  • Billiards and table tennis activities
  • Indoor Pool
  • Fitness Center
  • Meeting Rooms
Hotel with indoor pool and recreational facilities
FromUS$ 69 /nightSelect
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 By Ihg
8.4
Great
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 By Ihg
MapRestaurants within walking distance200m
  • Indoor swimming pool available year-round
  • On-site casino offers entertainment options
  • Fitness centre for leisure and wellness
  • Indoor Pool
  • Casino
  • Fitness Centre
Hotel with indoor pools, fitness centre, and spa facilities
FromUS$ 144 /nightSelect
Quality Inn Cape Girardeau North
8.0
Great
Quality Inn Cape Girardeau North
MapNearby Cape Girardeau River1km
  • Seasonal outdoor swimming pool
  • Complimentary continental breakfast daily
  • 24-hour front desk service
  • Outdoor pool
  • Free parking
  • Daily housekeeping
Affordable hotel with essential amenities for travelers
FromUS$ 67 /nightSelect
Fairfield By Marriott Inn & Suites Cape Girardeau
Fairfield By Marriott Inn & Suites Cape Girardeau
MapClose to several dining options7km
  • Saltwater indoor swimming pool
  • Family-friendly guest rooms
  • Access to fitness center
  • Indoor Pool
  • Fitness Centre
  • Saltwater Pool
Hotel featuring family rooms and leisure amenities
FromUS$ 114 /nightSelect
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
MapNearby Missouri Botanical Garden1.5km
  • Indoor swimming pool available year-round
  • Fitness center for active guests
  • Air-conditioned rooms for comfort
  • Indoor pool
  • Fitness center
  • 24-hour front desk
Modern hotel offering leisure amenities and comfort
FromUS$ 102 /nightSelect
Hampton Inn Cape Girardeau I-55 East, Mo
8.4
Great
Hampton Inn Cape Girardeau I-55 East, Mo
MapProximity to dining options100m
  • Indoor swimming pool and fitness centre
  • Family-friendly rooms and amenities
  • Seven restaurants within walking distance
  • Indoor Pool
  • Fitness Centre
  • Dining Options
Hotel with family-friendly features and local dining access
FromUS$ 133 /nightSelect
Town House Inn Cape Girardeau
7.6
Very good
Town House Inn Cape Girardeau
MapNext to restaurant300m
  • Pet-friendly accommodations available
  • 24-hour front desk service
  • Flat-screen TVs in rooms
  • 24-hour reception
  • Flat-screen TV
  • Pet-friendly
Hotel offering essential amenities for leisure travelers
FromUS$ 60 /nightSelect
Courtyard By Marriott Cape Girardeau Downtown
8.2
Great
Courtyard By Marriott Cape Girardeau Downtown
MapHistoric district ambiance300m
  • On-site bar with varied drinks selection
  • Unique historical features enhance guest experience
  • Convenient downtown location near attractions
  • Fitness Centre
  • On-site Bar
  • Event Spaces
Hotel blending modern comfort with unique historical charm
FromUS$ 124 /nightSelect
The Riverview
The Riverview
MapAccess to local attractions13km
  • Comfortable rooms with river views
  • Dining options for diverse tastes
  • 24-hour front desk service
  • Restaurant
  • Bar
  • Electric vehicle charging
Hotel with elegant dining and stunning river views
FromUS$ 145 /nightSelect
Candlewood Suites Cape Girardeau, An Ihg Hotel
8.0
Great
Candlewood Suites Cape Girardeau, An Ihg Hotel
MapNear Capaha Park300m
  • Indoor swimming pool available all year
  • Well-equipped fitness centre onsite
  • Pet-friendly rooms for travelers with pets
  • Indoor pool
  • Fitness centre
  • Golf course
Hotel offering convenient amenities for leisure and relaxation
FromUS$ 159 /nightSelect
Drury Conference
Drury Conference
MapProximity to local attractions9km
  • Relax at the on-site spa and wellness centre
  • Enjoy a variety of breakfast options available
  • Pet-friendly policy for travelers with pets
  • Spa & wellness
  • Fitness centre
  • Indoor pool
Hotel offering extensive leisure facilities and dining options
Select
Romantic Creekside Retreat With Fireplace And Deck
Romantic Creekside Retreat With Fireplace And Deck
MapNatural garden setting200m
  • Outdoor fireplace for cozy evenings
  • Garden views from private balcony
  • On-site picnic spots for relaxation
  • Outdoor seating
  • Private check-in
  • Bicycle parking
Charming hotel offering nature-inspired retreat options
FromUS$ 207 /nightSelect
The Little Cape Lofted Cottage On Winding Creek In Nature
The Little Cape Lofted Cottage On Winding Creek In Nature
MapPicturesque natural setting14km
  • Cozy two-bedroom cottage retreat
  • Outdoor patio with fireplace
  • Scenic garden views surrounded by nature
  • Outdoor fireplace
  • Private entrance
  • Barbecue area
Charming holiday park with outdoor dining areas
FromUS$ 213 /nightSelect
Euro Style Tiny Home With Deck
Euro Style Tiny Home With Deck
MapCape Girardeau Regional Airport14km
  • Two-bedroom layout with private entrance
  • Outdoor fireplace for cozy relaxation
  • Fully equipped kitchen for convenience
  • Outdoor dining
  • Garden terrace
  • Barbecue area
Tiny home resort offering unique outdoor living experience
FromUS$ 207 /nightSelect
Purple Tiny Home With Fire Pit And Nature
Purple Tiny Home With Fire Pit And Nature
MapNatural setting for outdoor activities14km
  • Outdoor fireplace for cozy evenings
  • Garden views enhance relaxation
  • Air-conditioned with kitchenette
  • Outdoor dining
  • Garden view
  • Fire pit
Charming tiny home with nature immersion and comfort
FromUS$ 165 /nightSelect
Enchanted Mermaid A-Frame, Creek, Fire Pit, Pet Friendly
Enchanted Mermaid A-Frame, Creek, Fire Pit, Pet Friendly
MapBoulder Creek setting200m
  • Outdoor fireplace with seating area
  • Pet-friendly rooms with garden views
  • Private check-in and check-out services
  • Outdoor fireplace
  • Private parking
  • Hiking trails
Pet-friendly holiday park with outdoor activities
FromUS$ 219 /nightSelect
Show more

Price range for hotels in Cape Girardeau

A world of accommodation options awaits, from budget-friendly stays to luxurious retreats, with prices suited to every traveler's dream vacation.

⬆️ The highest price
USD 219
⬇️ The lowest price
USD 60
💸 Average price for
4-star hotels
USD 145
3-star hotels
USD 111

Best hotels in Cape Girardeau

Based on guest reviews over the last 12 months

Historic Riverfront Escape:
Family Friendly Fun:
Comfort on a Budget:
Convenient Medical Stay:
Modern Downtown Vibes:
Nature Lovers Retreat:
Business Traveler Essential:
Extended Stay Experience:

How to get to Cape Girardeau

A list of all available types of transport

Airports
Cape Girardeau Regional (CGI)

FAQs about hotels in Cape Girardeau

We hope that the answers to these questions will help you plan your trip

Are there hotels in Cape Girardeau with unique views?
The Riverview offers scenic views of the Mississippi River and is a popular choice for guests seeking picturesque surroundings. The Courtyard By Marriott Cape Girardeau Downtown also provides nice views of the city skyline.
Which hotels in Cape Girardeau are ideal for couples?
The Drury Plaza Hotel Cape Girardeau Conference Center is known for its romantic ambiance and evening socials. The River View provides a cozy atmosphere for couples looking to relax by the river. Average nightly rates for couple-friendly hotels range from $110 to $180.

Hotel Options in Cape Girardeau, Missouri

This guide provides factual information on 14 hotels in Cape Girardeau, focusing on pricing, peak seasons, and local specifics to help inform your accommodation choices.

Typical nightly rates range from $85 to $150 USD.

There are 14 hotels available in Cape Girardeau.

Peak travel seasons are spring and fall.

Local taxes and fees add approximately 10% to room rates.

Most hotels are within 5 km of the Cape Girardeau Riverfront and downtown attractions.

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